Harrison's Principles of Internal Medicine !
* Expanded, modernized illustration program with more than 800 brand-new, additional illustrations—a 40% increase over the previous edition. This valuable new collection includes even more great depictions of pathophysiological processes, decision-speeding algorithms, clinical photographs, essential radiology images, an atlas of EKG tracings, and full color depictions of key pathological specimens—all designed to enhance learning and clinical application of the chapter material.
* Brand new, reader-friendly text design optimizes the full-color format. Even faster access to acclaimed features such as the Approach to the Patient boxes and Treatment boxes, graduated colors in tables to facilitate at-a-glance reference, illustration and table citations highlighted in bold, and numerous other changes speed you through the great Harrison's content quicker than ever.
* An expanded, innovative focus on global health. Harrison's 17th edition features brand new chapters such as"Global Considerations in Medicine" by Jim Kim and Paul Farmer, and the"Global Epidemiology of Cardiovascular Disease". In addition, many chapters feature a brand new Global Considerations icon, which identifies important epidemiological, diagnostic, and therapeutic distinctions between global regions to aid in the diagnosis and management of specific diseases.
* NEW Global Advisory Board comprised of 11 prominent medical experts from Asia, Europe, and South America.
* Revision of the popular On Line Learning Center, which offers more skill-sharpening self-assessment questions and answers, plus additional case studies for helping you apply Harrison's content to the daily care of patients.
* Bonus companion DVD features:
o 36 new"e-chapters" that cover vital topics in medical education, residency training, and clinical practice
o Over 500 brand-new radiological, laboratory, and clinical images, including complete atlases of hematologic specimens; radiological imaging in neurological, rheumatologic, pulmonary, and cardiovascular disease; rashes associated with fever; EKG interpretations; renal disease specimens and urinalysis; live biopsies; and much more
o State-of-the-art video clips of key diagnostic studies in cardiac and endoscopic imaging, plus video animations of the pathophysiological process of atherosclerosis
o An Image Bank of nearly all the illustrations contained in the parent text—ideal for use in lectures and presentations

Chapter-by-chapter coverage of why this is the best Harrison's yet!

* Over 40 chapters new to this edition, including"Health Disparities,""Quality and Safety in Patient Care,""The Biology of Psychiatric Disorders,""Hospital Neurology,""Electrophysiology in Neurological Diagnosis,""Clinical Management of Obesity," and"Approach to Heart Murmurs"
* Important new chapter on the Principles of Global Health and Medicine, reflecting key organizational, administrative and clinical issues of this increasingly influential area
* NEW section on Regenerative Medicine provides a leading-edge overview of this increasingly critical specialty in chapters such as"Stem Cell Biology,""Application of Stem Cell Biology to Clinical Medicine,""Hematopoietic Stem Cell Therapy," and"Tissue Engineering"
* The classic Introduction to Clinical Medicine section features a dramatic and timely revision, with great new chapters on Global Issues in Medicine, and new e-chapters addressing Patient Safety and Quality, Ethics in Medicine, and The Economics of Medicine; Health Disparities, and more.
* Cardinal Manifestations of Diseases section includes a new e-chapter,"Atlas of Skin Diseases," plus new chapters on"Hypercalcemia and Hypocalcemia" and on the neurological and nervous system manifestations of internal disease.
* Cardiology section features in-depth, brand new chapters on electrocardiography; the basic biology of the cardiovascular system; the worldwide epidemiology of heart disease; a great new review of the biology and clinical recognition of heart murmurs; and the metabolic syndrome, which addresses the current health crisis of obesity, heart disease, and diabetes.
* Pulmonary Diseases section features newly authored, state-of-the-art chapters on asthma and pneumonia; plus a brand new e-chapter on chest radiology that provides a complete and very useful atlas of radiographs and CT studies of a wide range of chest diseases.
* Nephrology section includes a brand-new chapter,"Cellular and Molecular Biology of the Kidney," that places the physiology and pathophysiology of renal disease into a coherent diagnostic and treatment framework; also included is a brand new e-chapter,"Atlas of Renal Pathology and Urinalysis," which includes numerous full-color pathological examples of common and rare kidney diseases.
* Oncology/Hematology section features, all-new and timely coverage of targeted anti-tumor therapies, and new treatment approaches to antiplatelet, anticoagulant, and fibrinolytic therapy, plus an entirely retooled section on Hemostasis that reflects critical new developments.
* Gastroenterology/Hepatology section includes two brand new chapters,"Common Diseases of the Colon and Anorectum" and"Mesenteric Vascular Insufficiency," and a thoroughly revised chapter,"Cirrhosis and Its Complications"; a new e-chapter,"Atlas of Liver Biopsies", which shows full color depiction of liver pathologies; and an completely updated chapter on the evolving knowledge base of the"Genetic and Metabolic Liver Diseases".
* Infectious Diseases section features an extensive collection of brand new pathological and radiological images and includes a huge number of rewritten and exhaustively updated chapters, covering the latest advances in the management of key diseases such as pneumonia, shigellosis, malaria, hospital-acquired and drug resistant infections, tuberculosis, and more. The HIV/AIDS chapter, an acknowledged classic worldwide, has been completely updated by the team of Fauci and Lane.
* Rheumatology section includes completely rewritten chapters on"Sarcoidosis,""Amyloidosis,""Osteoarthritis," and"Gout and Other Crystal Arthropathies," as well as a new e-chapter:"Atlas of Clinical Imaging in the Vasculitis Syndromes".
* Endocrine section features a state-of-the-art chapter on diabetes; a completely revised chapter on pheochromocytoma that emphasizes the genetic causes of these tumors; plus a valuable new e-chapter, the"Atlas of Metabolic Disorders"; and more.
* Neurology section includes great new chapters such as"Essential Tremor and Movement Disorders,""Peripheral Neuropathy," and"Neurologic Problems in Hospitalized Patients; and the Biology of Psychiatric Disorders by the leading authorities in the world.


PART 1 Introduction to Clinical Medicine

1 The Practice of Medicine.
The Editors

2 Global Issues in Medicine.
Jim Yong Kim / Paul Farmer

3 Decision-Making in Clinical Medicine.
Daniel B. Mark

4 Screening and Prevention of Diseases.
Gary J. Martin

5 Principles of Clinical Pharmacology.
Dan M. Roden

6 Women's Health.
Andrea Dunaif

7 Medical Disorders during Pregnancy.
Robert L. Barbieri / John T. Repke

8 Medical Evaluation of the Surgical Patient.
Wei C. Lau / Kim A. Eagle

9 Geriatric Medicine.
Lisa B. Caruso / Rebecca A. Silliman

10 Complementary and Alternative Medicine.
Stephen E. Straus

11 Palliative and End-of-Life Care.
Ezekiel J. Emanuel / Joshua Hauser / Linda L. Emanuel

e1 The Safety and Quality of Health Care. pdf
David W. Bates

e2 Economic Considerations in the Practice of Medicine.
David Meltzer

e3 Racial and Ethnic Disparities in Health Care.
Joseph R. Betancourt / David Blumenthal

e4 Ethical Issues in Clinical Medicine.
Bernard Lo

PART 2 Cardinal Manifestations and Presentation of Diseases

SECTION 1 PAIN

12 Pain: Pathophysiology and Management.
Howard L. Fields / Joseph B. Martin

13 Chest Discomfort.
Thomas H. Lee

14 Abdominal Pain.
William Silen

15 Headache.
Peter J. Goadsby / Neil H. Raskin

16 Back and Neck Pain.
John W. Engstrom

SECTION 2 ALTERATIONS IN BODY TEMPERATURE

17 Fever and Hyperthermia.
Charles A. Dinarello / Reuven Porat

18 Fever and Rash.
Elaine T. Kaye / Kenneth M. Kaye

e5 Atlas of Rashes Associated with Fever.
Elaine T. Kaye / Kenneth M. Kaye

19 Fever of Unknown Origin.
Jeffery A. Gelfand / Michael V. Callahan

20 Hypothermia and Frostbite.
Daniel F. Danzl

SECTION 3 NERVOUS SYSTEM DYSFUNCTION

21 Syncope.
Mark D. Carlson

22 Dizziness and Vertigo.
Robert B. Daroff

23 Weakness and Paralysis.
Michael J. Aminoff

24 Gait and Balance Disorders.
Lewis Sudarsky

25 Numbness, Tingling, and Sensory Loss.
Michael J. Aminoff / Arthur K.Asbury

26 Confusion and Delirium.
S. Andrew Josephson / Bruce L. Miller

e6 Memory Loss.
Thomas D. Bird / Bruce L. Miller

27 Aphasia, Memory Loss, and Other Focal Cerebral Disorders.
M.-Marsel Mesulam

28 Sleep Disorders.
Charles A. Czeisler / John W. Winkleman / Gary S. Richardson

SECTION 4 DISORDERS OF EYES, EARS, NOSE, AND THROAT

29 Disorders of the Eye.
Jonathan C. Horton

30 Disorders of Smell, Taste, and Hearing.
Anil K. Lalwani

31 Pharyngitis, Sinusitis, Otitis, and Other Upper Respiratory Infections.
Michael A. Rubin / Ralph Gonzales / Merle A. Sande

32 Oral Manifestations of Disease.
Samuel C. Durso

e7 Atlas of Oral Manifestations of Disease.
Samuel C. Durso / Janet A. Yellowitz

SECTION 5 ALTERATIONS IN CIRCULATORY AND RESPIRATORY FUNCTION

33 Dyspnea and Pulmonary Edema.
Richard M. Schwartzstein

34 Cough and Hemoptysis.
Steven E. Weinberger / David A. Lipson

35 Hypoxia and Cyanosis.
Eugene Braunwald

36 Edema
Eugene Braunwald / Joseph Loscalzo

e8 Approach to the Patient with a Heart Murmur.
Patrick O'Gara / Eugene Braunwald

37 Palpitations.
Joseph Loscalzo

SECTION 6 ALTERATIONS IN GASTROINTESTINAL FUNCTION

38 Dysphagia.
Raj K. Goyal

39 Nausea, Vomiting, and Indigestion.
William L. Hasler

40 Diarrhea and Constipation.
Michael Camilleri / Joseph A. Murray

41 Weight Loss.
Carol M. Reife

42 Gastrointestinal Bleeding.
Loren Laine

43 Jaundice.
Daniel S. Pratt / Marshall M. Kaplan

44 Abdominal Swelling and Ascites.
Robert M. Glickman / Roshini Rajapaksa

SECTION 7 ALTERATIONS IN RENAL AND URINARY TRACT FUNCTION

45 Azotemia and Urinary Abnormalities. pdf
Bradley M. Denker / Barry M. Brenner

e9 Atlas of Urinary Sediments and Renal Biopsies.
Agnes B. Fogo / Eric G. Neilsen

46 Fluid and Electrolyte Disturbances.
Gary G. Singer / Barry M. Brenner

47 Hypercalcemia and Hypocalcemia.
Sundeep Khosla

48 Acidosis and Alkalosis.
Thomas B. DuBose, Jr.

SECTION 8 ALTERATIONS IN SEXUAL FUNCTION AND REPRODUCTION

49 Sexual Dysfunction.
Kevin T. McVary

50 Hirsutism and Virilization.
David A. Ehrmann

51 Menstrual Disorders and Pelvic Pain.
Janet E. Hall

SECTION 9 ALTERATIONS IN THE SKIN

52 Approach to the Patient with a Skin Disorder.
Thomas J. Lawley / Kim B. Yancey

53 Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders
Calvin O. McCall / Thomas J. Lawley

54 Skin Manifestations of Internal Disease.
Jean L. Bolognia / Irwin M. Braverman

55 Immunologically Mediated Skin Diseases.
Kim B. Yancey / Thomas J. Lawley

56 Cutaneous Drug Reactions.
Jean-Claude Roujeau / Robert S. Stern / Bruce C. Wintroub

57 Photosensitivity and Other Reactions to Light.
David R. Bickers

e10 Atlas of Skin Manifestations of Internal Disease.
Thomas J. Lawley / Stephen Templeton

SECTION 10 HEMATOLOGIC ALTERATIONS

58 Anemia and Polycythemia.
John W. Adamson / Dan L. Longo

59 Bleeding and Thrombosis. pdf
Barbara A. Konkle

60 Enlargement of Lymph Nodes and Spleen.
Patrick H. Henry / Dan L. Longo

61 Disorders of Granulocytes and Monocytes.
Steven M. Holland and John I. Gallin

e11 Atlas of Peripheral Blood Smears.
Dan L. Longo

PART 3 Genetics and Disease

62 Principles of Human Genetics.
J. Larry Jameson / Peter Kopp

63 Chromosome Disorders.
Terry Hassold / Stuart Schwartz

64 The Practice of Genetics in Clinical Medicine.
Susan Miesfeldt / J. Larry Jameson

65 Gene Therapy in Clinical Medicine.
Katherine A. High

PART 4 Regenerative Medicine

66 Stem Cell Biology.pdf
Minoru S. H. Ko

67 Applications of Stem Cell Biology in Clinical Medicine.
Jack A. Kessler

68 Hematopoietic Stem Cells.
David T. Scadden / Dan L. Longo

69 Tissue Engineering.
Jennifer Anderson /Joseph P. Vacanti

PART 5 Nutrition

70 Nutritional Requirements and Dietary Assessment.
Johanna Dwyer

71 Vitamin and Trace Mineral Deficiency and Excess.
Robert M. Russell / Paolo M. Suter

72 Malnutrition and Nutritional Assessment.
Douglas C. Heimburger

73 Enteral and Parenteral Nutrition Therapy.
Bruce R. Bistrian / David F. Driscoll

74 Biology of Obesity.
Jeffrey S. Flier / Eleftheria Maratos-Flier

75 Evaluation and Management of Obesity.
Robert F. Kushner

76 Eating Disorders.
B. Timothy Walsh

PART 6 Oncology and Hematology

SECTION 1 NEOPLASTIC DISORDERS

77 Approach to the Patient with Cancer.
Dan L. Longo

78 Prevention and Early Detection of Cancer.
Otis W. Brawley / Barnett S. Kramer

79 Cancer Genetics.
Pat J. Morin / Jeffrey M. Trent / Francis S. Collins / Bert Vogelstein

80 Cancer Cell Biology and Angiogenesis.
Robert G. Fenton / Dan L. Longo

81 Principles of Cancer Treatment.
Edward A. Sausville / Dan L. Longo

82 Infections in Patients with Cancer.
Robert Finberg

83 Cancer of the Skin.
Arthur J. Sober / Hensin Tsao / Carl V. Washington

84 Head and Neck Cancer.
Everett E. Vokes

85 Neoplasms of the Lung.
John D. Minna / Joan H. Schiller

86 Breast Cancer.
Marc E. Lippman

87 Gastrointestinal Tract Center.
Robert J. Mayer

88 Tumors of the Liver and Biliary Tree.
Brian I. Carr

89 Pancreatic Cancer.
Yu Jo Chua / David Cunningham

90 Bladder and Renal Cell Carcinomas.
Howard I. Scher / Robert J. Motzer

91 Benign and Malignant Diseases of the Prostate.
Howard I. Scher

92 Testicular Cancer.
Robert J. Motzer / George J. Bosl

93 Gynecologic Malignancies.
Robert C. Young

94 Soft Tissue and Bone Sarcomas and Bone Metastases.
Shreyaskumar R. Patel / Robert S. Benjamin

95 Carcinoma of Unknown Primary. pdf
Gauri R. Varadhachary /James L. Abbruzzese

96 Paraneoplastic Syndromes: Endocrinologic/Hematologic.
J. Larry Jameson / Bruce E. Johnson

97 Paraneoplastic Neurologic Syndromes.
Joseph Dalmau / Myrna R. Rosenfeld

e12 Thymoma.
Dan L. Longo

e13 Late Consequences of Cancer and Its Treatment.
Michael C. Perry / Dan L. Longo

SECTION 2 HEMATOPOIETIC DISORDERS

98 Iron Deficiency and Other Hypoproliferative Anemias.
John W. Adamson

99 Disorders of Hemoglobin.
Edward J. Benz

100 Megaloblastic Anemia.
A. Victor Hoffbrand

101 Hemolytic Anemias and Anemias due to Acute Blood Loss.
Lucio Luzzatto

102 Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes.
Neal S. Young

103 Polycythemia Vera and Other Myeloproliferatve Diseases
Jerry L. Spivek

104 Acute and Chronic Myeloid Leukemia.
Meir Wetzler /John C. Byrd / Clara D. Bloomfield

105 Malignancies of Lymphoid Cells.
Dan L. Longo

106 Plasma Cell Disorders.
Nikhil C. Munshi / Dan L. Longo / Kenneth C. Anderson

107 Transfusion Biology and Therapy.
Jeffery S. Dzieczkowski / Kenneth C. Anderson

108 Hematopoietic Cell Transplantation.
Frederick R. Applebaum

DISORDERS OF HEMOSTASIS

109 Disorders of Platelets and Vessel Wall.
Barbara A. Konkle

110 Coagulation Disorders.
Valder Arruda / Katherine High

111 Thrombosis Venous.
F.R. Rosendaal / H.R. Büller

112 Antiplatelet, Anticoagulant, and Fibrinolytic Drugs.
Jeffery L. Weitz

PART 7 Infectious Diseases

SECTION 1 BASIC CONSIDERATIONS IN INFECTIOUS DISEASES

113 Introduction to Infectious Diseases: Host-Pathogen Interactions.
Lawrence C. Madoff / Dennis L. Kasper

114 Molecular Mechanisms of Microbial Pathogenesis.
Gerald B. Pier

115 Approach to the Acutely Ill Infected Febrile Patient.
Tamar F. Barlam / Dennis L. Kasper

116 Immunization Principles and Vaccine Use.
Gerald T. Keusch / Kenneth J. Bart / Mark Miller

117 Health Advice for International Travel.
J.S. Keystone / P.. Kozarsky

e14 Laboratory Diagnosis of Infectious Diseases.
Alexander J. McAdam / Andrew B. Onderdonk

SECTION 2 CLINICAL SYNDROMES: COMMUNITY-ACQUIRED INFECTIONS

118 Infective Endocarditis.
Adolf W. Karchmer

119 Infections of the Skin, Muscle, and Soft Tissues.
Dennis L. Stevens

120 Osteomyelitis.
Jeffrey Parsonnet

121 Intraabdominal Infections and Abscesses.
Miriam J. Baron / Dennis L. Kasper

122 Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning.
Joan R. Butterton / Stephen B. Calderwood

123 Clostridium difficile-Associated Disease, Including Pseudomembranous Colitis.
Dale N. Gerding / Stuart Johnson

SECTION 3

124 Sexually Transmitted Infections: Overview and Clinical Approach.
King K. Holmes

e15 Infectious Complications of Bites and Burns.
Lawrence C. Madoff / Florencia Pereyra

SECTION 3 CLINICAL SYNDROMES: NOSOCOMIAL INFECTIONS

125 Health Care-Associated Infections.
Robert A. Weinstein

126 Infections in Transplant Recipients.
Robert Finberg /Joyce Fingeroth

SECTION 4 APPROACH TO THERAPY FOR BACTERIAL DISEASES

127 Treatment and Prophylaxis of Bacterial Infections.
Gordon L. Archer / Ronald E. Polk

SECTION 5 DISEASES CAUSED BY GRAM-POSITIVE BACTERIA

128 Pneumococcal Infections.
Daniel M. Musher

129 Staphylococcal Infections.
Franklin D. Lowy

130 Strepococcal and Enterococcal Infections.
Michael R. Wessels

131 Diphtheria and Other Infections Caused by Corynebacteria and Related Species.
William R. Bishai / Jack R. Murphy

132 Infections Caused by Listeria monocytogenes.
Elizabeth L. Hohmann / Daniel A. Portnoy

133 Tetanus.
Elias Abrutyn

134 Botulism.
Elias Abrutyn

135 Gas Gangrene and Other Clostridial Infections.
Dennis L. Kasper /Lawrence C. Madoff

SECTION 6 DISEASES CAUSED BY GRAM-NEGATIVE BACTERIA

136 Meningococcal Infections.
Lee M. Wetzler

137 Gonococcal Infections.
Sanjay Ram / Peter A. Rice

138 Moraxella Infections.
Daniel M. Musher

139 Haemophilus Infections.
Timothy F. Murphy

140 Infections Due to the HACEK Group and Miscellaneous Gram-Negative Bacteria.
Tamar F. Barlam / Dennis L. Kasper

141 Legionella Infection.
Miguel Sabria / Victor L. Yu

142 Pertussis and Other Bordetella Infections.
Scott A. Halperin

143 Diseases Caused by Gram-Negative Enteric Bacilli.
Thomas A. Russo / James R. Johnson

144 Helicobacter Pylori Infections.
John C. Atherton / Martin J. Blaser

145 Infections Due to Pseudomonas Species and Related Organisms.
Reuben Ramphal

146 Salmonellosis.
David A. Pegues / Samuel I. Miller

147 Shingellosis.
Philippe Sansonetti / Jean Bergounioux

148 Infections Due to Campylobacter and Related Species.
Martin J. Blaser

149 Cholera and Other Vibrioses.
Matthew K. Waldor / Gerald T. Keusch

150 Brucellosis.
Michael J. Corbel / Nicholas J. Beeching

151 Tularemia.
Richard F. Jacobs / Gordon E. Schutze

152 Plague and Other Yersnia Infections.
David T. Dennis / Grant L. Campbell

153 Bartonella Infections, Including Cat-Scratch Disease.
David H. Spach / Emily Darby

154 Donovanosis.
Gavin Hart

SECTION 7 MISCELLANEOUS BACTERIAL INFECTIONS

155 Nocardiosis.
Gregory A. Filice

156 Actinomycosis.
Thomas A. Russo

157 Infections Due to Mixed Anaerobic Organisms.
Dennis L. Kasper / Ronit Cohen-Poradosu

SECTION 8 MYCOBACTERIAL DISEASES

158 Tuberculosis.
Mario C. Raviglione / Richard J. O'Brien

159 Leprosy (Hansen's Disease).
Robert H. Gelber

160 Nontuberculous Mycobacteria.
C. Fordham von Reyn

161 Antimycobacterial Agents.
Richard J. Wallace / David E. Griffith

SECTION 9 SPIROCHETAL DISEASE

162 Syphilis.
Sheila A. Lukehart

163 Endemic Treponematoses.
Sheila A. Lukehart

164 Leptospirosis.
Peter Speelman / Rudy Harkskeerl

165 Relapsing Fever.
David T. Dennis

166 Lyme Borreliosis.
Allen C. Steere

SECTION 10 DISEASES CAUSED BY RICKETTSIA, MYCOPLASMA, AND CHLAMYDIA

167 Rickettsial Diseases.
David H. Walker / Didier Raoult / J. Stephen Dumler / Thomas Marrie

168 Infections Due to Mycoplasmas.
William M. McCormack

169 Chlamydial Infections.
Walter E. Stamm

SECTION 11 VIRAL DISEASES: GENERAL CONSIDERATIONS

170 Medical Virology.
Fred Wang and Elliott Kieff

171 Antiviral Chemotherapy, Excluding Antiretroviral Drugs.
Lindsey R. Baden / Raphael Dolin

SECTION 12 INFECTIONS DUE TO DNA VIRUSES

172 Herpes Simplex Viruses.
Lawrence Corey

173 Varicella-Zoster Virus Infections.
Richard J. Whitley

174 Epstein-Barr Virus Infections, Including Infectious Mononucleosis. pdf
Jeffery I. Cohen

175 Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8.
Martin S. Hirsch

176 Molluscum Contagiosum, Monkeypox and Other Poxviruses Excluding Smallpox Virus.
Fred Wang

177 Parvovirus Infections.
Kevin E. Brown

178 Human Papillomavirus Infections.
Richard C. Reichman

SECTION 13 INFECTIONS DUE TO DNA AND RNA RESPIRATORY VIRUSES

179 Common Viral Respiratory Infections and Severe Acute Respiratory Syndrome (SARS).
Raphael Dolin

180 Influenza.
Raphael Dolin

SECTION 14 INFECTIONS DUE TO HUMAN IMMUNODEFICIENCY VIRUS AND OTHER HUMAN RETROVIRUSES

181 The Human Retroviruses.
Dan L. Longo /Anthony S. Fauci

182 Human Immunodeficiency Virus Disease: AIDS and Related Disorders.
Anthony S. Fauci / H. Clifford Lane

SECTION 15 INFECTIONS DUE TO RNA VIRUSES

183 Viral Gastroenteritis.
Umesh D. Parashar / Roger I. Glass

184 Enterovirus and Reoviruses Infections.
Jeffery I. Cohen

185 Measles (Rubeola).
Anne Gershon

186 Rubella (German Measles).
Anne Gershon

187 Mumps.
Anne Gershon

188 Rabies and Other Rhabdovirus Infections.
Alan C. Jackson / Eric C. Johannsen

189 Infections Caused by Arthropod and Rodent-Borne Viruses.
Clarence J. Peters

190 Ebola and Marburg Viruses.
Clarence J. Peters

SECTION 16 FUNGAL AND ALGAL INFECTIONS

191 Diagnosis and Treatment of Fungal Infections.
John E. Edwards

192 Histoplasmosis.
Chadi A. Hage / L. Joseph Wheat

193 Coccidioidomycosis.
Neil M. Ampel

194 Blastomycosis.
Stanley W. Chapman

195 Cryptococcosis.
Arturo Casadevall

196 Candidiasois.
John E. Edwards

197 Aspergillosis.
David W. Denning

198 Mucormycosis.
Alan M. Sugar

199 Miscellaneous Mycoses and Algal Infections.
Stanley W. Chapman / Donna C. Sullivan

200 Pneumocystis Infection.
A. Geroge Smulian /Peter D. Walzer

SECTION 17 PROTOZOAL AND HELMINTHIC INFECTIONS: GENERAL CONSIDERATIONS

e16 Laboratory Diagnosis of Parasitic Infections.
Sharon L. Reed / Charles E. Davis

201 Agents Used to Treat Parasitic Infections.
Thomas A. Moore

e17 Pharmacology of Agents Used to Treat Parasitic Infections.
Thomas A. Moore

SECTION 18 PROTOZOAL INFECTIONS

202 Ambiasis and Infection with Free-Living Amebas.
Sharon L. Reed

203 Malaria.
Nicholas J. White / Joel G. Breman

204 Babesiosis.
Jeffery Gelfand

e18 Atlas of Blood Smears of Malaria and Babesiosis.
Nicholas J. White / Joel G. Breman

205 Leishmaniasis.
Barbara L. Herwaldt

206 Trypanosomiasis.
Louis V. Kirchhoff

207 Toxoplasma Infections.
Lloyd H. Kasper

208 Protozoal Intestinal Infections and Trichomoniasis.
Peter F. Weller

SECTION 19 HELMINTHIC INFECTIONS

209 Trichinella and Other Tissue Nematodes.
Peter F. Weller

210 Intestinal Nematodes.
Peter F. Weller /Thomas B. Nutman

211 Filarial and Related Infections.
Peter F. Weller / Thomas B. Nutman

212 Schistosomiasis and Other Trematode Infections.
Adel A.F. Mahmoud

213 Cestodes.
A. Clinton White, Jr. / Peter F. Weller

PART 8 Bioterrorism and Clinical Medicine

Z214 Microbioterrorism.
H. Clifford Lane / Anthony S. Fauci

215 Chemical Bioterrorism.
Charles G. Hurst / Jonathan Newmark / James A. Romano

216 Radiation Bioterrorism.
Zelig A. Tochner / Eli Glatstein

PART 9 Disorders of Cardiovascular System

SECTION 1 INTRODUCTION TO CARDIOVASCULAR DISORDERS

217 Basic Biology of the Cardiovascular System.
Joseph Loscalzo / Peter Libby / Eugene Braunwald

218 Epidemiology of Cardiovascular Disease.
Thomas A. Gaziano / J. Michael Gaziano

219 Approach to the Patient with Possible Cardiovascular Disease.
Eugene Braunwald

SECTION 2 DIAGNOSIS OF CARDIOVASCULAR DISORDERS

220 Physical Examination of the Cardiovascular System.
Robert A. O'Rourke /Eugene Braunwald

221 Electrocardiography.
Ary L. Goldberger

e19 Atlas of Electrocardiography.
Ary L. Goldberger

222 Noninvasive Cardiac Imaging: Echocardiography, Nuclear Cardiology, and MRI/CT Imaging.
Rick Nishimura / Raymond J. Gibbons / James F. Glockner /A. Jamil Tajik

e20 Atlas of Noninvasive Cardiac Imaging.
Rick Nishimura

223 Diagnostic Cardiac Catheterization and Angiography.
Donald S. Baim

SECTION 3 DISORDERS OF RHYTHM

224 Principles of Electrophysiology.
Gordon F. Tomaselli

225 The Bradyarrhythmias. pdf
Gordon F. Tomaselli

226 The Tachyarrhythmias.
Francis Marchlinksi

e21 Atlas of Cardiac Arrhythmias.
Ary L. Goldberger

SECTION 4 DISORDERS OF THE HEART

227 Heart Failure and Cor Pulmonale.
Douglas L. Mann

228 Cardiac Transplantation and Prolonged Assisted Circulation.
Sharon A. Hunt

229 Congenital Heart Disease in the Adult.
John S. Child

230 Valvular Heart Disease.
Patrick O'Gara / Eugene Braunwald

231 Cardiomyopathy and Myocarditis.
Joshua Wayne / Eugene Braunwald

232 Pericardial Disease.
Eugene Braunwald

233 Tumors and Trauma of the Heart.
Eric H. Awrty / Wilson S. Colucci

234 Cardiac Manifestations of Systemic Disease.
Eric H. Awrty / Wilson S. Colucci

SECTION 5 VASCULAR DISEASE

235 The Pathogenesis, Prevention, and Treatment of Atherosclerosis.
Peter Libby

e22 Atlas of Atherosclerosis.
Peter Libby

236 The Metabolic Syndrome.
Robert H. Eckel

237 Ischemic Heart Disease.
Elliott M. Antman / Andrew P. Selwyn/ Eugene Braunwald / Joseph Loscalzo

238 Unstable Angina and Non-ST-Elevation Myocardial Infarction.
Christopher P. Cannon / Eugene Braunwald

239 ST-Segment Elevation Myocardial Infarction.
Elliott M. Antman / Eugene Braunwald

240 Percutaneous Coronary Intervention.
Donald S. Baim

e23 Atlas of Percutaneous Revascularization.
Donald S. Baim

241 Hypertensive Vascular Disease.
Ted A. Kotchen

242 Diseases of the Aorta.
Mark A. Creager / Joseph Loscalzo

243 Vascular Diseases of the Extremities.
Mark A. Creager / Joseph Loscalzo

244 Pulmonary Hypertension.
Stuart Rich

PART 10 Disorders of the Respiratory System

SECTION 1 DIAGNOSIS OF RESPIRATORY DISORDERS

245 Approach to the Patient with Disease of the Respiratory System.
David A. Lipson / Steven E. Weinberger

246 Disturbances of Respiratory Function.
Steven E. Weinberger /Ilene M. Rosen

247 Diagnostic Procedures in Respiratory Diseases.
Scott Manaker / Steven E. Weinberger

e24 Atlas of Chest Imaging.
Patricia Kritek / John J. Reilly, Jr.

SECTION 2 DISEASES OF THE RESPIRATORY SYSTEM

248 Asthma.
Peter J. Barnes

249 Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia.
Joel N. Kline / Gary W. Hunninghake

250 Environmental Lung Disease.
Frank E. Speizer / John R. Balmes

251 Pneumonia.
Lionel A. Mandell / Richard Wunderink

252 Bronchiectasis and Lung Abscess.
Gregory Tino / Steven E. Weinberger

253 Cystic Fibrosis.
Richard C. Boucher

254 Chronic Obstructive Pulmonary Disease.
John J. Reilly, Jr. / Edwin K. Silverman / Steven D. Shapiro

255 Interstitial Lung Diseases.
Talmadge E. King, Jr.

256 Deep Venous Thrombosis and Pulmonary Thromboembolism.
Samuel Z. Goldhaber

257 Disorders of the Pleura and Mediastinum.
Richard W. Light

258 Disorders of Ventilation.
Eliot A. Phillipson

259 Sleep Apnea.
Neil J. Douglas

260 Lung Transplantation.
Elbert P. Trulock

PART 11 Critical Care Medicine

SECTION 1 RESPIRATORY CRITICAL CARE

261 Principles of Critical Care Medicine.
John P. Kress / Jesse B. Hall

262 Acute Respiratory Distress Syndrome.
Bruce D. Levy / Steve D. Shapiro

263 Mechanical Ventilatory Support.
Edward P. Ingenito

SECTION 2 SHOCK AND CARDIAC ARREST

264 Approach to the Patient with Shock.
Ronald V. Maier

265 Severe Sepsis and Septic Shock.
Robert S. Munford

266 Cardiogenic Shock and Pulmonary Edema.
Judith S. Hochman / David H. Ingbar

267 Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death.
Robert J. Myerberg / Agustin Castellanos

SECTION 3 NEUROLOGIC CRITICAL CARE

268 Coma.
Allan H. Ropper

269 Neurologic Critical Care, Including Hypoxic-Ischemic Encephalopathy and Subarachnoid Hemorrhage.
J. Claude Hemphill / Wade S. Smith

SECTION 4 ONCOLOGIC EMERGENCIES

270 Oncologic Emergencies.
Rasim Gucalp / Janice Dutcher

PART 12 Disorders of the Kidney and Urinary Tract

271 Cellular and Molecular Biology of the Kidney.
Alfred L. George / Eric G. Neilson

272 Adaptation of the Kidney to Renal Injury.
Raymond C. Harris / Eric G. Neilson

273 Acute Renal Failure.
Kathleen D. Liu / Glenn M. Chertow

274 Chronic Kidney Disease.
Joanne M. Bargman / Karl Skorecki

275 Dialysis in the Treatment of Renal Failure.
Kathleen D. Liu / Glenn M. Chertow

276 Transplantation in the Treatment of Renal Failure.
Charles B. Carpenter / Edgar L. Milford / Mohamed H. Sayegh

277 Glomerular Diseases.
Julia B. Lewis / Eric G. Neilson

278 Polycystic Kidney Disease and Other Inherited Tubular Disorders.
David J. Salant / Parul S. Patel

279 Tubulointerstitial Diseases of the Kidney. pdf
Alan S. L. Yu / Barry M. Brenner

280 Vascular Injury to the Kidney.
Kamal F. Badr / Barry M. Brenner

281 Nephrolithiasis.
John R. Asplin / Fredric L. Coe / Murray J. Favus

282 Urinary Tract Infections, Pyelonephritis, and Prostatitis.
Walter E. Stamm

283 Urinary Tract Obstruction.
Julian L. Seifter / Barry M. Brenner

PART 13 Disorders of the Gastrointestinal System

SECTION 1 DISORDERS OF THE ALIMENTARY TRACT

284 Approach to the Patient with Gastrointestinal Disease.
William L. Hasler / Chung Owyang

285 Gastrointestinal Endoscopy.
Louis Michel Wong Kee Song / Mark Topazian

e25 Video Atlas of Gastrointestinal Endoscopy. Mark Topazian

286 Diseases of the Esophagus.
Raj. K. Goyal

287 Peptic Ulcer Disease and Related Disorders.
John Del Valle

288 Disorders of Absorption.
Henry J. Binder

289 Inflammatory Bowel Disease.
Sonia Friedman / Richard S. Blumberg

290 Irritable Bowel Syndrome.
Chung Owyang

291 Diverticular Disease and Common Anorectal Disorders.
Susan L. Gearhart

292 Mesenteric Vascular Insufficiency.
Susan L. Gearhart

293 Acute Intestinal Obstruction.
Susan L. Gearhart / William Silen

294 Acute Appendicitis and Peritonitis.
Susan L. Gearhart / William Silen

SECTION 2 LIVER AND BILIARY TRACT DISEASE

295 Approach to the Patient with Liver Disease.
Marc Ghany /Jay H. Hoofnagle

296 Evaluation of Liver Function.
Daniel S. Pratt / Marshall M. Kaplan

297 The Hyperbilirubinemias.
Allan W. Wolkoff

298 Acute Viral Hepatitis.
Jules L. Dienstag

299 Toxic and Drug-Induced Hepatitis.
Jules L. Dienstag

300 Chronic Hepatitis.
Jules L. Dienstag

301 Alcoholic Liver Disease.
Mark E. Malliard / Michael F. Sorrell

302 Cirrhosis and Its Complications.
Bruce R. Bacon

e26 Atlas of Liver Biopsies.
Jules L. Dienstag

303 Genetic, Metabolic, and Infiltrative Diseases Affecting the Liver.
Bruce R. Bacon

304 Liver Transplantation.
Jules L. Dienstag /Raymond T. Chung

305 Diseases of the Gallbladder and Bile Ducts.
Norton J. Greenberger / Gustav Paumgartner

SECTION 3 DISORDERS OF THE PANCREAS

306 Approach to the Patient with Pancreatic Disease.
Phillip P. Toskes / Norton J. Greenberger

307 Acute and Chronic Pancreatitis.
Norton J. Greenberger / Phillip P. Toskes

PART 14 Disorders of the Immune System, Connective Tissue, and Joints

SECTION 1 THE IMMUNE SYSTEM IN HEALTH AND DISEASE

308 Introduction to the Immune System.
Barton F. Haynes / Kelly A. Soderberg / Anthony S. Fauci

309 The Major Histocompatability Complex.
Gerald T. Nepom

310 Primary Immune Deficiency Diseases.
Max D. Cooper / Harry W. Schroeder, Jr.

e27 Primary Immunodeficiencies Associated with or Secondary to Other Diseases.
Max D. Cooper

SECTION 2 DISORDERS OF IMMUNE-MEDIATED INJURY

311 Allergies, Anaphylaxis, and Systemic Mastocytosis.
K. Frank Austen

312 Autoimmunity and Autoimmune Diseases.
Peter E. Lipsky / Betty Diamond

313 Systemic Lupus Erythematosus.
Bevra Hannahs Hahn

314 Rheumatoid Arthritis.
Peter E. Lipsky

315 Acute Rheumatoid Fever.
Jonathan R. Carapetis

316 Systemic Sclerosis (Scleroderma) and Related Disorders.
John Varga

317 Sjögren's Syndrome.
Haralampos M. Moutsopoulos

318 The Spondyloarthritides.
Joel D. Taurog

319 The Vasculitis Syndromes.
Carol A. Langford / Anthony S. Fauci

e28 Atlas of Clinical Imaging of the Vasculitic Diseases.
Carol A. Langford / Anthony S. Fauci

320 Behçet's Syndrome.
Haralampos M. Moutsopoulos

321 Relapsing Polychondritis.
Carol A. Langford /Bruce C. Gilliland

322 Sarcoidosis.
Robert P. Baughman /Elyse E. Lower

323 Familial Mediterranean Fever and Other Hereditary Recurrent Fevers. Daniel L. Kastner

324 Amyloidosis.
David C. Seldin / Martha Skinner

SECTION 3 DISORDERS OF THE JOINTS AND ADJACENT TISSUES

325 Approach to Articular and Musculoskeletal Disorders.
John J. Cush / Peter E. Lipsky

326 Osteoarthritis.
David T. Felson

327 Gout and Other Crystal Arthropathies. pdf
H. Ralph Schumacher / Lan X. Chen

328 Infectious Arthritis.
Lawrence C. Madoff

329 Fibromyalgia.
Carol A. Langford /Bruce C. Gilliland

330 Arthritis Associated with Systemic Disease and Other Arthritides.
Carol A. Langford / Bruce C. Gilliland

331 Periarticular Disorders of the Extremities.
Carol A. Langford / Bruce C. Gilliland

PART 15 Endocrinology and Metabolism

SECTION 1 ENDOCRINOLOGY

332 Principles of Endocrinology.
J. Larry Jameson

333 Disorders of the Anterior Pituitary and Hypothalamus.
Shlomo Melmed / J. Larry Jameson

334 Disorders of the Neurohypophysis.
Gary L. Robertson

335 Disorders of the Thyroid Gland.
J. Larry Jameson / Anthony P. Weetman

336 Disorders of the Adrenal Cortex.
Gordon H. Williams / Robert G. Dluhy

337 Pheochromocytoma.
Hartmut P.H. Neumann

338 Diabetes Mellitus.
Alvin C. Powers

339 Hypoglycemia.
Phillip E. Cryer

340 Disorders of the Testes and the Male Reproductive System.
Shalender Bhasin / J. Larry Jameson

341 Disorders of the Ovary and Female Reproductive Tract.
Janet E. Hall

342 The Menopause Transition and Postmenopausal Hormone Therapy.
JoAnn E. Manson /Shari S. Bassuk

343 Disorders of Sex Development.
John C. Achermann / J. Larry Jameson

344 Endocrine Tumors of the Gastrointestinal Tract and Pancreas.
Robert T. Jensen

345 Disorders Affecting Multiple Endocrine Neoplasia Syndromes.
Camillo Jimenez / Robert Gagel

SECTION 2 DISORDERS OF BONE AND MINERAL METABOLISM

346 Bone and Mineral Metabolism in Health and Disease.
F. Richard Bringhurst / Marie B. Demay / Stephen M. Krane / Henry M. Kronenberg

347 Diseases of the Parathyroid Gland and Other Hyper-and Hypocalcemia Disorders.
John T. Potts, Jr.

348 Osteoporosis.
Robert Lindsay / Felicia Cosman

349 Paget Disease and Other Dysplasias of Bone.
Murray J. Favus /Tamara J. Vokes

SECTION 3 DISORDERS OF INTERMEDIARY METABOLISM

350 Disorders of Lipoprotein Metabolism.
Daniel J. Rader / Helen H. Hobbs

351 Hemochromatosis.
Lawrie W.Powell

352 The Porphyrias.
Robert J. Desnik / Kenneth H. Astrin

353 Disorders of Purine and Pyrimidine Metabolism.
Robert L. Wortmann

354 Wilson Disease.
George J. Brewer

355 Lysosomal Storage Disease.
Robert J. Hopkin / Gregory A. Grabowski

356 Glycogen Storage Diseases and Other Inherited Disorders of Carbohydrate Metabolism.
Yuan-Tsong Chen

357 Heritable Disorders of Connective Tissue.
Darwin J. Prockop / Malwina Czarny-Ratajczak

358 Inherited Disoders of Amino Acid Metabolism in Adults.
Nicola Longo

359 Inherited Defects of Membrane Transport.
Nicola Longo

e29 Atlas of Clinical Manifestations of Metabolic Diseases.
J. Larry Jameson

PART 16 Neurologic Disorders

SECTION 1 DIAGNOSIS OF NEUROLOGIC DISORDERS

360 Mechanisms of Neurologic Disorders.
Stephen Hauser / M. Flint Beal

361 Approach to the Patient with Neurologic Disease.
Daniel H. Lowenstein / Joseph B. Martin / Stephen L. Hauser

362 Neuroimaging in Neurologic Disorders.
William P. Dillon

e30 Atlas of Neuroimaging.
Andre Furtado / William P. Dillon

e31 Electrodiagnostic Studies of Nervous System Disorders: EEG and EMG.
Michael J. Aminoff

e32 Technique of Lumbar Puncture.
Elizabeth Robbins / Stephen L. Hauser

SECTION 2 DISEASES OF THE CENTRAL NERVOUS SYSTEM

363 Seizures and Epilepsy.
Daniel H. Lowenstein

364 Cerebrovascular Diseases.
Wade S. Smith / Joey English / S. Claiborne Johnston

365 Dementia.
Thomas D. Bird / Bruce L. Miller

366 Parkinson's Disease and Other Extrapyramidal Disorders.
Mahlon R. DeLong / Jorge L. Juncos

367 Hyperkinetic Movement Disorders.
C. Warren Olanow

368 Ataxic Disorders.
Roger N. Rosenberg

369 Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases.
Robert H. Brown, Jr.

370 Disorders of the Autonomic Nervous System.
Phillip A. Low / John W. Engstrom

371 Trigeminal Neuralgia, Bell's Palsy, and Other Cranial Nerve Disorders.
M. Flint Beal / Stephen L. Hauser

372 Diseases of the Spinal Cord.
Stephen L. Hauser / Allan H. Ropper

373 Concussion and Other Head Injuries.
Allan H. Ropper

374 Primary and Metastatic Tumors of the Nervous System.
Stephen M. Sagar / Mark A. Israel

375 Multiple Sclerosis and Other Demyelinating Diseases.
Stephen L. Hauser / Douglas S. Goodin

376 Meningitis, Encephalitis, Brain Abscess, and Empyema.
Karen L. Roos / Kenneth L. Tyler

377 Chronic and Recurrent Meningitis.
Walter J. Koroshetz / Morton N. Swartz

378 Prion Diseases.
Stanley B. Prusiner / Bruce Miller

SECTION 3 NERVE AND MUSCLE DISORDERS

379 Peripheral Neuropathy.
Vinay Chaudhry

380 Guillain-Barre Syndrome and Other Immune-Mediated Neuropathies.
Steven L. Hauser / Arthur K. Asbury

381 Mysathenia Gravis and Other Diseases of the Neuromuscular Junction. Daniel B. Drachman

382 An Approach to Muscular Dystrophy and Other Muscle Diseases.
Robert H. Brown, Jr. / Anthony A. Amato / Jerry R. Mendell

383 Polymyositis, Dermatomyositis, and Inclusion Body Myositis.
Marinos C. Dalakas

e33 Special Issues in Inpatient Neurologic Consultation.
S. Andrew Josephson / Martin A. Samuels

SECTION 4 CHRONIC FATIGUE SYNDROME

384 Chronic Fatigue Syndrome.
Stephen E. Straus

SECTION 5 PSYCHIATRIC DISORDERS

385 Biology of Psychiatric Disorders.
Steve Hyman / Eric Kandel

386 Mental Disoders.
Victor I. Reus

SECTION 6 ALCOHOLISM AND DRUG DEPENDENCY

387 Alcohol and Alcoholism.
Marc A. Schuckit

388 Opioid Drug Abuse and Dependence.
Mark A. Schuckit

389 Cocaine and Other Commonly Abused Drugs.
Jack H. Medelson / Nancy K. Mello

390 Nicotine Addiction.
David M. Burns

PART 17 Poisoning, Drug Overdose, and Envenomation

e34 Heavy Metal Poisoning.
Howard Hu

e35 Poisoning and Drug Overdosage.
Christopher H. Linden / Michael J. Burns / Mark B. Mycyk

391 Disorders Caused by Reptile Bites and Marine Animal Exposures.
Paul Auerbach / Robert Norris

e36 Ectoparasite Infestations and Arthropod Bites and Stings.
Richard J. Pollack / James H. Maguire

SUMMARIES OF CHAPTERS e1 TO e36.

APPENDIX

Laboratory Values of Clinical Importance.
Alexander Kratz / Michael A. Pesce / Daniel J. Fink


Editia 17
Numar pagini:2650
Anul apartiei: 2008

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